Nocturnal acid breakthrough on proton pump inhibitor therapy: to treat or not to treat.
نویسندگان
چکیده
OPINION STATEMENT Nocturnal acid breakthrough is misunderstood and infrequently requires treatment in everyday practice. There are important subgroups of patients in whom esophageal reflux occurs in the presence of nocturnal acid breakthrough in which treatment may be needed.
منابع مشابه
Nocturnal acid breakthrough: consequences and confronting
Nocturnal Acid Breakthrough is defined as the appearance of gastric acid in the antrum of pH<4 overnight for a period longer than one hour during the administration of proton pump inhibitors. The prevalence of this phenomenon ranges between 69-79% in normal volunteers and patients with gastroesophageal reflux disease respectively. It typically appears in the second 6-hour period after the eveni...
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عنوان ژورنال:
- Current treatment options in gastroenterology
دوره 11 1 شماره
صفحات -
تاریخ انتشار 2008